Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry a
protein found invertebrates such ashumans ,mice andchickens
Etymologies
Sorry, no etymologies found.
Examples
-
(DOR) promotes the processing of Aβ precursor protein (APP) by BACE1 and γ-secretase, but not that of Notch, N-cadherin or APLP.
-
(DOR) promotes the processing of Aβ precursor protein (APP) by BACE1 and γ-secretase, but not that of Notch, N-cadherin or APLP.
-
Scientists blocked surface molecules, proteins called N-cadherin, on the neural crest cells that are involved in forming contacts between cells.
-
It is expected that inhibition of N-cadherin would have the same the effect in cancer cells, which also move in groups during metastasis.
-
Green, mCD8-GFP, labeling LN processes; red, synaptotagmin-HA, a marker for presynaptic terminals; blue, nc82 or N-cadherin staining, highlighting glomerular structures.
-
To determine the functional relevance of these findings, we tested the effects of ERK and PI3K inhibitors on cell proliferation induced by Wnt. As shown in N-cadherin overexpression negatively regulates ERK and PI3K signalling.
-
Finally, we found that the decreased cell survival induced by N-cadherin overexpression was reversed by Wnt and antagonized by PI3K inhibition.
-
Mechanisms by which N-cadherin decreases cell survival.
-
The altered cell survival induced by N-cadherin overexpression is Wnt - and PI3K/Akt-dependent.
-
Tibias from 1.5 month old female N-cadherin transgenic and wild type mice and primary osteoblasts isolated from calvarias by sequential collagenase digestion were obtained as described
Comments
Log in or sign up to get involved in the conversation. It's quick and easy.