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Examples
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Cramer thinks Allos is a great speculative small-cap stock which has as its catalyst the expected Food and Drug Adminstration's approval of its orphan drug called Pralatrexate, or PDX, which treats peripheral T-cell lymphoma.
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Pralatrexate was discovered at Memorial Sloan Cancer Center in New York and later in-licensed by Allos in 2002 during my tenure as CEO.
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Pralatrexate is a novel targeted antifolate designed to accumulate preferentially in cancer cells.
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The results, outlined in a poster titled "Cytotoxicity of Pralatrexate, a Novel Synthetic Antifolate, in Human Cancer Cell Lines (abstract #1686)," demonstrate anticancer activity of pralatrexate in nine of 15 human cell lines tested.
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Pralatrexate has orphan drug designation and fast track designation in the U.S. for the treatment of patients with T-cell lymphoma and orphan medicinal product designation in Europe for the treatment of PTCL.
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(Pralatrexate in patients with Relapsed Or refractory PEripheral T-cell Lymphoma) enrolled a total of 115 patients with relapsed or refractory PTCL, 109 of whom are considered evaluable for response according to the trial protocol.
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Pralatrexate is a novel targeted antifolate designed to accumulate preferentially in cancer cells.
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Pralatrexate is a novel targeted antifolate designed to accumulate preferentially in cancer cells.
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The results were outlined in a poster presentation (Cytotoxicity of Pralatrexate, a Novel Synthetic Antifolate, in Human Cancer Cell Lines, abstract #1686) and highlights anticancer activity for pralatrexate in nine of 15 human cell lines tested.
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Pralatrexate has orphan drug designation and fast track designation in the U.S. for the treatment of patients with T-cell lymphoma and orphan medicinal product designation in Europe for the treatment of PTCL.
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