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Examples
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Here are some of the approved and tentative antivirals: Lamivudine, Nevirapine, Zidovudine, Didanosine, Stavudine, Efavirenz, Lopinavir, Ritonavir and Tenofovir Disoproxil Fumarate.
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Here are some of the approved and tentative antivirals: Lamivudine, Nevirapine, Zidovudine, Didanosine, Stavudine, Efavirenz, Lopinavir, Ritonavir and Tenofovir Disoproxil Fumarate.
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"Ritonavir looks like it's increasing blood fat levels, not only when people are fasting but also after (eating) meals," one of the researchers, Associate Professor Katherine Samaras, told AAP.
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The post-meal surge in blood fat levels experienced by the Ritonavir group may be one of the factors explaining why people being treated with this type of drug are at a higher risk of getting heart disease, she said.
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During the research, 20 volunteers without HIV infection were split into groups which took either Ritonavir or Raltegravir for one month.
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The findings showed that Ritonavir, an older, commonly used drug, which was formerly linked to heart risk, had more adverse effects on people's metabolisms than the newer drug,
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The second Phase II study in 79 HIV infected treatment naïve adults is evaluating the safety and efficacy of GS 9350 boost Atazanavir compared to Ritonavir boost Atazanavir each in combination with Truvada.
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Ritonavir is currently the only boosting agent available for HIV therapy.
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Matrix's second-line products selected for the 2009 UNITAID-CHAI projects include heat-stable Lopinavir / Ritonavir, Tenofovir and two fixed-dose combinations that use Tenofovir.
ITnews 2009
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The first study is evaluated our quad drug-the fixed dose regimen of Truvada, elvitegravir, and GS9350 versus Atripla-and the second is a head to head study of GS9350, our novel boosting agent versus Ritonavir.
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