SIADH

Fifty years ago the syndrome of inappropriate secretion of anti-diuretic hormone was described in a lung cancer patient and the term SIADH Syndrome of inappropriate anti-diuretic hormone secretion entered the medical vocabulary.

SIADH or SIAD-where did the "h" go and does it matter? james gaulte 2007

Fifty years ago the syndrome of inappropriate secretion of anti-diuretic hormone was described in a lung cancer patient and the term SIADH Syndrome of inappropriate anti-diuretic hormone secretion entered the medical vocabulary.

Archive 2007-05-01 james gaulte 2007

Regardless, there seems to be some combination of excessive fluid intake and fluid retention by whatever mechanisms-and I think a SIADH type picture is an appealing possible mechanism-resulting in a clinical situation where what you do not need is normal saline.

More on marathoner's hyponatremia james gaulte 2007

I thought this was something new rather than some subtlety I have just missed but a perfunctory Google search leads to more than one not- very- recent article than used that term in the sense of SIADH being a subset of SIAD.

SIADH or SIAD-where did the "h" go and does it matter? james gaulte 2007

It is suggested by the authors of the AJM article than this may be a form of SIADH or the syndrome of inappropriate secretion of ADH and while excessive ingestion of water may be necessary it is not sufficient to cause the condition.

Archive 2007-05-01 james gaulte 2007

A recent article in NEJM informs the readers that only about one-third of cases of SIADH have non-suppressed levels of arginine vasopressin so that the term "Syndrome of Inappropriate Antidiuresis " is more correct or appropriate.

Archive 2007-05-01 james gaulte 2007

Regardless, there seems to be some combination of excessive fluid intake and fluid retention by whatever mechanisms-and I think a SIADH type picture is an appealing possible mechanism-resulting in a clinical situation where what you do not need is normal saline.

Archive 2007-05-01 james gaulte 2007

SIADH or SIAD-where did the "h" go and does it matter?

Archive 2007-05-01 james gaulte 2007

A recent article in NEJM informs the readers that only about one-third of cases of SIADH have non-suppressed levels of arginine vasopressin so that the term "Syndrome of Inappropriate Antidiuresis " is more correct or appropriate.

SIADH or SIAD-where did the "h" go and does it matter? james gaulte 2007

I thought this was something new rather than some subtlety I have just missed but a perfunctory Google search leads to more than one not- very- recent article than used that term in the sense of SIADH being a subset of SIAD.

Archive 2007-05-01 james gaulte 2007