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Examples
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& Co., which in 2006 acquired RNA-interference specialist Sirna Therapeutics for $1.1 billion.
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Sirna has laid claim to a huge patent estate in the RNAi field.
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The former Sirna chairman and former head of R&D at pharmaceutical giant GlaxoSmithKline is a firm believer in Sirna's new approach.
Merck Makes $1 Billion Bet On Nobel-Winning Discovery Update -- Merck's $1 Billion Bet Matthew Herper 2006
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Sirna is working to develop drugs utilizing a new technology known as RNAi.
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Alnylam shares closed Tuesday up 18% on news of the Sirna buyout but erased half of those gains later in the week after a number of Street analysts downgraded the stock.
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Yesterday, Merck announced it was buying Sirna for $1.1 billion, more than a 100% premium to Sirna's $470 million market capitalization.
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Sirna has been in the news of late because Andrew Fire and Craig Mello, the discoverers of the technology upon which Sirna's drugs are based--RNA interference, or RNAi-- won a Nobel Prize for medicine last month.
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And with GlaxoSmithKline, Sirna inked a deal to develop drugs for the treatment of respiratory diseases such as asthma and allergic rhinitis.
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The $1.1 billion buyout offer caps a remarkable turnaround for Sirna.
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As of last week, Sirna had been in discussions with a number of large pharmaceutical firms about a collaboration, says a spokesman.
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