acetylserotonin love



from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun organic chemistry The N-acetyl derivative of serotonin; it is an intermediate in the biosynthesis of melatonin from serotonin


Sorry, no etymologies found.


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  • N-acetylserotonin could stimulate TrkB even when BDNF was not present, both in cell culture dishes and in mice, Ye and his colleagues found.

    RedOrbit News - Technology 2010

  • Melatonin's immediate precursor, N-acetylserotonin, was not previously thought to have effects separate from those of melatonin or serotonin.

    RedOrbit News - Technology 2010

  • Ye's laboratory is now investigating the mechanism by which N-acetylserotonin activates TrkB.

    RedOrbit News - Technology 2010

  • One of the most common strains of laboratory mice (C57Bl6) is deficient in making N-acetylserotonin and melatonin and develops retinal degeneration.

    RedOrbit News - Technology 2010

  • "We were surprised to find that N-acetylserotonin, but not serotonin or melatonin, can activate TrkB."

    RedOrbit News - Technology 2010

  • The authors observed that in the retinas of mice that produce adequate melatonin, TrkB is turned on at night, a pattern that matches the appearance of N-acetylserotonin.

    RedOrbit News - Technology 2010

  • He says that N-acetylserotonin has a short lifetime in the body but similar compounds that are more stable may be useful in treating neurological diseases.

    RedOrbit News - Technology 2010

  • Now an Emory team has shown that N-acetylserotonin can stimulate the same circuits in the brain activated by the growth factor BDNF (brain-derived neurotrophic factor).

    RedOrbit News - Technology 2010

  • The discovery has implications for the study of how some antidepressants function and may also explain previous observations that N-acetylserotonin has antidepressant activity in animal models of depression.

    RedOrbit News - Technology 2010


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