Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry The formation of
fatty tissue;lipogenesis
Etymologies
Sorry, no etymologies found.
Examples
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This report is a follow-up to the many excellent studies from Nikhil Dhurandar’s group, which first suggested that the rather common human Ad36 virus may play a role in adipogenesis (formation of fat cells).
Dr. Sharma’s Obesity Notes » Blog Archive » Obesity Goes Viral?
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The researchers examined a biological process called adipogenesis, using cultures of a cell line called 3T3-L1, which is often used to study fat cells.
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While the exact actions of this drug, and more generally the thiazolidinediones (TZD) class of drugs are beyond the scope of this post, it is important to understand that these drugs seem to upregulate the production of healthy new fat cells (a process known as adipogenesis) - that is they make you fatter.
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Genetic manipulations in mice that increase or decrease fat formation have provided evidence that adipogenesis, meaning the generation of fat cells, delays other metabolic consequences of overeating.
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Vitamin K2 inhibits adipogenesis, osteoclastogenesis, and ODF/RANK ligand expression in murine bone marrow cell cultures.
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A recent in vitro study indicates that IGOB131, a novel seed extract of the traditional West African food plant Irvingia gabonensis, favorably impacts adipogenesis through a variety of critical metabolic pathways including PPAR gamma, leptin, adiponectin, and glycerol-3 phosphate dehydrogenase.
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This study demonstrates that EPA differentially modulates adipogenesis and lipid accumulation to suppress LD formation and size.
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(EE) and increased adipogenesis, without alterations in feeding or locomotor functions.
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Takahashi N, Goto T, Taimatsu A, Egawa K, Katoh S, et al. (2009) Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARgamma activation.
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Besides our basic research into the molecular mechanism of adipogenesis, we are also interested in identifying potential drug targets to treat obesity and metabolic diseases such as diabetes.
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