from The Century Dictionary.
- Characterized by the absence of ganglia.
from the GNU version of the Collaborative International Dictionary of English.
- adjective (Physiol.) Without ganglia.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective physiology Without
from Wiktionary, Creative Commons Attribution/Share-Alike License
Hirschsprung's Disease, also known as congenital megacolon or aganglionic megacolon is an abnormality in which the parasympathetic ganglion cells, (which control colon motility) are not developed within the colon walls in the early embryonic stages of development.
Bealer JF, Natuzzi ES, Buscher C, Ursell PC, Flake AW, Adzick NS, Harrison MR: Nitric oxide synthase is deficient in the aganglionic colon of patients with Hirschsprung's disease.