from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. An enzyme present in certain living tissues, including skeletal and heart muscle tissues, that catalyzes the breakdown of a fructose ester into triose sugars.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An enzyme, present in some tissue, that catalyses the conversion of phosphates of fructose to those of glyceraldehyde and dihydroxyacetone


aldol +‎ -ase (Wiktionary)


  • In order to metabolize fructose (and sucrose for that matter but thats simply because sucrose has fructose in it) the body does need to make a few enzymes primarily aldolase-B

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  • Hereditary Fructose Intolerance is a condition that results from a rare genetic inability to produce the aldolase-B enzyme which is necessary to the proper metabolizing of fructose despite the fact that it is already a simple sugar.

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  • It had been observed by Harland Wood's group at Western Reserve that when 14C-lactate or 14C-glycerol are fed to a fasted animal the labeling of the glucose units of liver glycogen was such as to suggest that triose-P isomerase had failed to equilibrate its two triose phosphate substrates during synthesis, or that the condensation reaction of FDP aldolase did not give equal labeling of the two halves of

    Irwin Rose - Autobiography

  • In a surprise result, the Schiffs bases of dihydroxyacetone-P and of FDP were found to precipitate with the protein of muscle aldolase in cold acid43.

    Irwin Rose - Autobiography

  • This property due to the stability of the Schiffs base intermediates in acid and the acid lability of the eneamin-Ps were used to determine their concentrations as intermediates in the aldolase reaction44.

    Irwin Rose - Autobiography

  • Protein levels for parasite pLDH (Standard Diagnostics, Kyonggi-do, Korea) and aldolase

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  • RDTs targeting other antigens (pLDH and aldolase) and quality microscopy should be used for malaria diagnosis.

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  • In contrast, all 9 samples had measurable levels of pLDH and aldolase.

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  • RDTs detecting parasite LDH or aldolase and quality microscopy should be use for malaria diagnosis in this region.

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  • It exploits the promiscuous aldolase activity of the enzyme macrophomate synthase (MPS) to add pyruvate enolate diastereoselectively to a wide range of structurally complex aldehydes.

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