Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- verb Present participle of
alkylate .
Etymologies
Sorry, no etymologies found.
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Examples
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In 2002, they discovered that the gene alteration makes brain cancer cells more responsive to anticancer drugs known as alkylating agents.
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For example, drugs known as alkylating agents are associated with the development of leukemia many years later.
Find Me A Cure 2008
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For women, alkylating agents such as cyclophosphamide Cytoxan lead to the highest incidence of ovarian failure.
A Baby at Last! Mark L. Fuerst 2010
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Some chemotherapy medicines, such as those in the alkylating agents group, can cause infertility.
A Baby at Last! Mark L. Fuerst 2010
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The current standard of care for malignant gliomas is surgical resection and radiotherapy followed by extended adjuvant treatment with the alkylating agent temozolomide.
I don't even know where to start with this one . . . - The Panda's Thumb 2007
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Heating, treatment with ultraviolet light or alkylating agents which destroy the infectious property of conventional viruses allow the survival of the infectious agents causing Kuru and related diseases.
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Three percent of the mothers exposed to radiation or treated with alkylating chemotherapy had a child with a genetic birth defect, compared with 3.5 percent of mothers who survived cancer, but weren't exposed to these treatments, the researchers found.
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While life-saving in many cases, radiotherapy and chemotherapy with alkylating agents, such as busulfan, cyclophosphamide and dacarbazine, can damage DNA.
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"We found that DNA damage from radiation and chemotherapy with alkylating agents are not associated with the risk of genetic birth defects in the offspring," said lead researcher Lisa Signorello, an associate professor of medicine at Vanderbilt University in Nashville.
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These include alkylating agents, particularly temozolomide (Temodar), topoisomerase I poisons (irinotecan [Camptosar], topotecan [Hycamtin]), and cross-linking drugs (platinum, mitomycin C [Mitozytrex, Mutamycin]).
MedPageToday.com - medical news plus CME for physicians 2010
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