Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun medicine A particular
tissue plasminogen activator , used to dissolveblood clots
Etymologies
Sorry, no etymologies found.
Support
Help support Wordnik (and make this page ad-free) by adopting the word alteplase.
Examples
-
In this study, the authors did a follow-up safety analysis from SITS-ISTR to assess the implementation of the longer time window after publication of the ECASS III and SITS-ISTR studies in September 2008, the effect on admission-to-treatment time, and to confirm or refute whether alteplase remains safe when given beyond 3 hours.
PhysOrg.com - latest science and technology news stories 2010
-
Findings showed that the proportion of patients receiving alteplase treatment within 3-4. 5 hours in the last quarter of 2009 was three times higher than in the first quarter of 2008
PhysOrg.com - latest science and technology news stories 2010
-
Philadelphia, USA, and Steven R Levine from State University of New York Health Science Center and School of Medicine, New York, USA, point out that despite the ample evidence of the efficacy and effectiveness of alteplase, neither the European Medicines Agency or the US Food and Drug Administration have approved alteplase for use in the extended time window.
PhysOrg.com - latest science and technology news stories 2010
-
Previous research from ECASS III and SITS-ISTR has shown the benefit and safety of alteplase treatment in the 3-4. 5 hour window after stroke.
PhysOrg.com - latest science and technology news stories 2010
-
Extension of the timeframe for alteplase treatment after acute stroke from 3 hours up to 4.5 hours is a safe option and has not resulted in delayed treatment of patients.
PhysOrg.com - latest science and technology news stories 2010
-
Reperfusion of ischaemic brain IV alteplase (0·9 mg / kg, at most 90 mg), With 10\% as a bolus followed by an Infusion Lasting 60 min: selected Patients within 3h of Onset of ischaemic Stroke Reduces the odds of death or Dependency at Final follow-up by 44\% 110 people (50-170) from death or Dependency for every 1000 treated
-
The available agents today are tissue-type plasminogen activator or alteplase (tPA), reteplase, tenecteplase, urokinase, anisoylated purified streptokinase activator complex, and streptokinase.
-
The mainstay of treatment in the last three to four years has been to dissolve the clot using a drug called tPA (alteplase).
-
Hacke W et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke.
BMJ Latest Articles 2009
-
Actilyse® (active ingredient: alteplase), is approved for use within 3 hours from the onset of ischaemic stroke.
Comments
Log in or sign up to get involved in the conversation. It's quick and easy.