Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A cytoprotective adjuvant used in cancer chemotherapy.

Etymologies

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Examples

  • For example, Dr. Movsas was the principal investigator of the largest national randomized study of a radioprotector, called amifostine, to reduce radiation injury in lung cancer patients.

    FinanzNachrichten.de: Aktuelle Nachrichten 2010

  • Ok, here's an interesting fact about the Apollo programme: the US astronauts reputedly took supplies of the radioprotective drug (now referred to as) amifostine.

    Jean Toad and swimming in space-time Gordon McCabe 2009

  • NASA were concerned about the occurrence of a solar flare en route to the moon; amifostine scavenges the free radicals caused by the passage of ionising radiation through cellular matter, and thereby reduces the chances of such radicals causing irreparable cellular damage.

    Jean Toad and swimming in space-time Gordon McCabe 2009

  • The company continues to selectively sell pantoprazole sodium, a generic version of Wyeth's heartburn drug Protonix, and amifostine injection, a generic version of MedImmune Oncology Inc. 's 500 milligram Ethyol injection.

    Sun Pharma Profit Drops 67% 2009

  • Sales and profit at the U.S. unit and at the parent were also hurt as the comparable quarter last year benefited from exclusive U.S. sales of two generic drugs - pantoprazole sodium and amifostine.

    Sun Pharma Profit Drops 67% 2009

  • To date, the only such prophylactic product to receive approval from the U.S. Food and Drug Administration (FDA) is Ethyol® (amifostine), which was originally discovered through the U.S. Army Research and Development Command's Anti-radiation Drug Development Program.

    unknown title 2011

  • To date, the only such prophylactic product to receive approval from the U.S. Food and Drug Administration (FDA) is Ethyol® (amifostine), which was originally discovered through the U.S. Army Research and Development Command's Anti-radiation Drug Development Program.

    unknown title 2011

  • To date, the only such prophylactic product to receive approval from the U.S. Food and Drug Administration (FDA) is Ethyol® (amifostine), which was originally discovered through the U.S. Army Research and Development Command's Anti-radiation Drug Development Program.

    unknown title 2011

  • Taken together, our results indicate that amifostine treatment modulates tumour angiogenesis by two apparently opposite mechanisms - the increased VEGF-A expression by tumour cells and the inhibition of EC capacity to respond to VEGF-A stimulation.

    BioMed Central - Latest articles S Dedieu 2010

  • Nevertheless, direct treatment of EC with amifostine impaired their ability to respond to exogenous VEGF-A, an effect that correlated to the down-regulation of VEGFR-2 expression, to the reduction in cell surface binding of VEGF-A and to the decreased phosphorylation of the downstream p42/44 kinases.

    BioMed Central - Latest articles S Dedieu 2010

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