aminocaproic

Trasylol costs $1,300 per use, compared with $44 for aminocaproic acid and $11 for tranexamic acid, says lead author Dennis Mangano, head of the Ischemia Research and Education Foundation in San Bruno, Calif.

Costly bypass medication may raise death risk later 2007

The new, multi-center international study compared the death rates of four groups of patients who had undergone bypass surgery: 1,072 given Trasylol, 834 given aminocaproic acid; 442 given tranexamic acid and 1,374 who didn't receive any medication to prevent excessive bleeding.

Costly bypass medication may raise death risk later 2007

The study found that 6% of patients who received Trasylol, or aprotinin, died within 30 days of surgery compared to 4% of patients who received tranexamic acid or aminocaproic acid.

Bayer Antibleeding Drug Takes Hit 2008

"This study could have been done by the company five to ten years ago," Dr. Hébert said, adding that Trasylol costs about $1,400 compared to about $4 for aminocaproic acid.

Bayer Antibleeding Drug Takes Hit 2008

The study data was gathered from patients who had surgery between 1996 and 2000, at more than 69 medical centers around the world, and received either Trasylol, aminocaproic acid, tranexamic acid, or no drug treatment.

Drug Alert - Trasylol Blamed For Lethal Injuries During Surgery 2006

The study's control group of 1,374 patients, received a placebo, while 1,295 patients received Trasylol, 883 others received aminocaproic, and 822 patients received tranexamic.

Drug Alert - Trasylol Blamed For Lethal Injuries During Surgery 2006

These agents could provide a superior replacement for the antifibrinolytic agents Trasylol® aprotinin, tranexamic acid and epsilon aminocaproic acid.

Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance 2011

Until its permanent withdrawal from the market in 2008, the antifibrinolytic Trasylol® (aprotinin) had been shown in a number of studies to be more effective at reducing blood loss than the other two commonly used agents, tranexamic acid (TXA) and epsilon aminocaproic acid (EACA).

Omeros Licenses Novel Antifibrinolytic Agents - Yahoo! Finance 2011

While there is some literature comparing the effectiveness of tranexamic acid (TXA) to epsilon aminocaproic acid (EACA) in cardiac procedures, there is currently no literature directly comparing TXA to EACA in orthopedic surgery.

BioMed Central - Latest articles 2010

While there is some literature comparing the effectiveness of tranexamic acid (TXA) to epsilon aminocaproic acid (EACA) in cardiac procedures, there is currently no literature directly comparing TXA to EACA in orthopedic surgery.

BioMed Central - Latest articles 2010