Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A topoisomerase inhibitor being studied as a possible cancer treatment.

Etymologies

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Examples

  • AS1413 (amonafide L-malate) is a DNA intercalator that induces apoptotic signalling by blocking Topoisomerase II binding to DNA.

    Marketwire - Breaking News Releases 2010

  • AS1413 (amonafide L-malate) was added to Antisoma's pipeline through the acquisition of

    StreetInsider.com News Articles 2010

  • AS1413 (amonafide L-malate) is a DNA intercalator that induces apoptotic signalling by blocking Topoisomerase II binding to DNA.

    Marketwire - Breaking News Releases 2010

  • * #3665 The novel DNA intercalator amonafide (AS1413) disrupts the cell cycle by mechanisms distinct from topo II inhibitors daunorubicin and etoposide (Senderovich et al.)

    Marketwire - Breaking News Releases 2010

  • AS1413 (amonafide L-malate) in secondary acute myeloid leukaemia (secondary AML) is now fully enrolled.

    StreetInsider.com News Articles 2010

  • * #3665 The novel DNA intercalator amonafide (AS1413) disrupts the cell cycle by mechanisms distinct from topo II inhibitors daunorubicin and etoposide (Senderovich et al.)

    Marketwire - Breaking News Releases 2010

  • AS1413 (amonafide L-malate) is a DNA intercalator that induces apoptotic signalling by blocking Topoisomerase II binding to DNA.

    Latest News from SYS-CON ITALIA 2009

  • ChemGenex has a second anticancer compound, amonafide dihydrochloride (Quinamed®) which is in phase 2 clinical development for various solid cancers, and a portfolio of assets in pre-clinical development.

    The Earth Times Online Newspaper 2009

  • ChemGenex has a second anticancer compound, amonafide dihydrochloride (Quinamed (R)) which is in phase 2 clinical development for various solid cancers, and a portfolio of assets in pre-clinical development.

    StreetInsider.com News Articles 2009

  • ChemGenex has a second anticancer compound, amonafide dihydrochloride (Quinamed®) which is in phase 2 clinical development for various solid cancers, and a portfolio of assets in pre-clinical development.

    Health News from Medical News Today 2009

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