Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry A particular
autocrine growth factor
Etymologies
Sorry, no etymologies found.
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Examples
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INNATE IMMUNITY keratinocyte express epidermal growth factors: amphiregulin
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Additive inhibition of HCA7 proliferation was observed with the combination of SC-236 and neutralising antibody to amphiregulin (AR), a soluble EGFR ligand.
BioMed Central - Latest articles Glen Doherty 2009
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Direct measurement of ligand shedding confirmed that LPA treatment stimulated shedding of multiple EGFR ligands, but paradoxically, IGF-1 had little effect on the shedding rate of any ligand, including amphiregulin.
Journal of Biological Chemistry current issue K. D. Rodland 2008
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Studies using anti-ligand antibodies showed that IGF-1 transactivation required amphiregulin production, whereas LPA was dependent on multiple ligands.
Journal of Biological Chemistry current issue K. D. Rodland 2008
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Instead, IGF-1 appeared to work by enhancing EGFR activation of Ras in response to constitutively produced amphiregulin.
Journal of Biological Chemistry current issue K. D. Rodland 2008
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