analytes

Fellows should be able to convey to other professionals the nature of the patients 'inborn error, the gene involved and its chromosomal location, if known, the treatment and, if possible, the analytes to follow to assure adequacy of therapy, and prognosis.

Laboratory Rotation 2010

Through time additional chemicals were added, and today approximately 140 analytes are monitored.

Archive 2008-05-01 2008

Through time additional chemicals were added, and today approximately 140 analytes are monitored.

Literary Warrant [30] 2008

In addition, two different approaches were applied to recover part of the potential information carried out by the protein analytes that showed a significant percentage of samples with values below detection limit in at least one of the groups (depressed, schizophrenics and controls), with the percentage of "censored values" differing between the groups.

PLoS ONE Alerts: New Articles Enrico Domenici et al. 2010

Box plots of individual analytes with high univariate significance.

PLoS ONE Alerts: New Articles Enrico Domenici et al. 2010

Multivariate analysis was also carried out to explore correlations within the dataset, and to identify whether multiple analytes could increase the discrimination between cases and controls.

PLoS ONE Alerts: New Articles Enrico Domenici et al. 2010

As each of the protein analytes is tested by a specific immunoassay, the resulting data have potentially different statistical properties and therefore different required data transformations prior to analysis.

PLoS ONE Alerts: New Articles Enrico Domenici et al. 2010

While one cannot completely rule out that the observed changes are arising from technical differences between sites in sampling procedures for instance, it is difficult to understand how these site effects could specifically impact only on a subset of correlated analytes.

PLoS ONE Alerts: New Articles Enrico Domenici et al. 2010

In addition, we have found some degree of correlation between analytes that significantly contributed to the separation between schizophrenic and control samples (not shown), suggesting that the difference in levels between disease and control samples maybe arise from a modulation of a common biological mechanism.

PLoS ONE Alerts: New Articles Enrico Domenici et al. 2010

The results obtained have highlighted a number of differences between cases and controls which is well above what could be expected under the null hypothesis, with several protein analytes that appeared to be specifically modulated in one of the two disease groups.

PLoS ONE Alerts: New Articles Enrico Domenici et al. 2010