from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. The replenishment of a deficiency
- n. An intermediate enzyme reaction that replaces a depleted vital compound
from The Century Dictionary and Cyclopedia
- n. The addition of what is lacking; specifically, in medicine, the filling up of a deficiency caused by loss of substance, as in wounds.
Sorry, no etymologies found.
Harvey thinks that repletio is an error of the translation reading anaplerosis for anaperosis.
To test the hypothesis that anaplerosis is important for insulin secretion, we lowered the activity of pyruvate carboxylase (PC), the major enzyme of anaplerosis in the beta cell.
The results confirm the central importance of PC and anaplerosis to generate metabolites from glucose that support insulin secretion and even suggest PC is important for insulin secretion stimulated by noncarbohydrate insulin secretagogues.