Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun The protein component of an enzyme, to which the coenzyme attaches to form an active enzyme.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry An inactive haloenzyme lacking a cofactor.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a protein that combines with a coenzyme to form an active enzyme

Etymologies

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Examples

  • The slow conformational change is responsible for the apparent tight binding of NADH to the apoenzyme but is too slow to participate in the catalytic cycle when the enzyme is rapidly turning over.

    Journal of Biological Chemistry current issue R. L. Burton 2008

  • (apoenzyme without flavin addition [8]) [8] 3.5 (apoenzyme with addition of FMN [8]) [8] 11.7

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  • [2] (apoenzyme is crystallized by dialysis method, using ammonium sulfate as the precipitant [18]) [18] Cloning

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  • (weaker binding to the apoenzyme than FAD [15]) [15] Metals, ions Additional information

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  • (most of the activity of the apoenzyme is reconstituted by the addition of FAD, FMN is a poor substitute for FAD [8]) [8] Crystallization

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