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Examples
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Alberts S, Hallum AV, Stratton-Custis M, Garcia D J, Gleason-Guzman M, et al. (2001) Phase I pharmacokinetic trial and correlative in vitro phase II tumor kinetic study of apomine (SR-45023A), a novel oral biphosphonate anticancer drug.
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Also, as their chemical structures are close to the apomine BP which presented aliphatic ester group, we suggested that their half-life will be close to that found for this drug (156 h with micromolar plasma concentration,
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