argatroban

One problem with this is that fondaparinux is not approved in the U.S.for treatment of HIT only argatroban and lepirudin are.

Should we consider HIT (heparin induced thrombocytopenia) in cases of DVT and PE? james gaulte 2007

One problem with this is that fondaparinux is not approved in the U.S.for treatment of HIT only argatroban and lepirudin are.

Archive 2007-01-01 james gaulte 2007

The study was a randomized, open-label, exploratory study comparing fixed-dose, SC desirudin vs. adjusted-dose, IV argatroban in 16 patients with clinically suspected HIT.

Medlogs - Recent stories 2010

In addition, there was the need for only one dose adjustment throughout the entire trial in patients randomized to desirudin, as compared to an average of 3.8 dose adjustments per patient in subjects randomized to IV argatroban.

Medlogs - Recent stories 2010

In addition, the cost of treatment with desirudin was about one-fifth the cost of treatment with argatroban.

Medlogs - Recent stories 2010

In the study, no thrombosis or major bleeds occurred in patients who received desirudin, and fewer dose adjustments were required for patients receiving desirudin compared with those receiving argatroban.

Medlogs - Recent stories 2010

The PREVENT-HIT study found that desirudin warrants further investigation as an alternative treatment for thrombosis prophylaxis in surgery patients with HIT. argatroban, the current standard of care.

Medlogs - Recent stories 2010

PREVENT-HIT is a randomized trial comparing fixed-dose, subcutaneous (SC) desirudin with adjusted-dose, intravenous (IV) argatroban in patients with clinically suspected heparin-induced thrombocytopenia (HIT).

Medlogs - Recent stories 2010

The cost of desirudin ($1,750) was about one-fifth the cost of argatroban ($8,250).

Medlogs - Recent stories 2010

Patients were randomized to desirudin 15 or 30 mg SC every 12 hours or IV argatroban in a 1: 1 ratio.

Medlogs - Recent stories 2010