Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A second-generation
antihistamine drug discovered in 1977.
Etymologies
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Examples
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(Compazine, others) and promethazine (Phenergan, others); antihistamines such as astemizole
Wii-volution 2009
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Lanzoprazole and astemizole specifically tag pathological oligomers of tau which form the core of neurofibrillary tangles (NFTs), a pathognomonic brain lesion in Alzheimer´s patients.
PhysOrg.com - latest science and technology news stories 2010
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Furthermore, experts argue that if the health ministry could in the past ban painkiller rofecoxib, diabetes drug phenformin, and anti-allergy drugs astemizole and terfenadine due to adverse effects based on global reports, why can't the same logic be applied in case of other drugs which have been banned globally?
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Lanzoprazole and astemizole specifically tag pathological oligomers of tau which form the core of neurofibrillary tangles (NFTs), a pathognomonic brain lesion in Alzheimer's patients.
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The interactions of lanzoprazole and astemizole with the anomalous tau aggregates were assessed by classical radioligand assays, combined with surface plasmon resonance, bioinformatic approaches and immunofluorescence studies on isolated PHFs and brain samples from Alzheimer's cases.
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Interestingly, lanzoprazole and astemizole, already approved for treatment of proton pump disorders and as an antihistamine respectively, specifically bind directly to aggregated variants of tau protein, paired helical filaments (PHFs) and NFTs in Alzheimer's brains.
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Atripla should not be taken with Hismanal® (astemizole), Vascor® (bepridil), Propulsid®
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Recognition and reporting of this arrhythmia in association with terfenadine, astemizole (Hismanal), cisapride (Propulsid), grepafloxacin (Raxar), and mibefradil (Posicor) ultimately led to the removal of these medications from the market.
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(Elavil), maprotiline (Ludiomil), and nefazodone (Serzone); antifungal medications such as fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral); phenothiazines such as prochlorperazine (Compazine, others) and promethazine (Phenergan, others); antihistamines such as astemizole (Hismanal); blood pressure medications such as bepridil
Wii-volution 2010
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