from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun pharmacology A non-stimulant drug used for the treatment of ADHD.


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  • ADHD drugs (e.g., amphetamine and methylphenidate-based medications, non-stimulants such as atomoxetine), however, are associated with a variety of side effects and are not always effective.


  • So, for most children and adults, the generics dextroamphetamine or methylphenidate are as safe and effective as the heavily-advertised, brand-name drugs like Adderall XR (an extended-release mix of amphetamine salts), Concerta (extended-release methylphenidate) or Strattera (atomoxetine) to treat ADHD symptoms.

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  • Although there is no conclusive evidence that atomoxetine causes aggressive behaviour or hostility, aggressive behaviour or hostility was more frequently observed in clinical trials among children and adolescents treated with atomoxetine compared to placebo (overall risk ratio of 1.33 – not statistically significant).


  • They include Adderall/Adderall XR (amphetamine/dextroamphetamine), Advair Diskus (fluticasone/salmeterol), Elidel (pimecrolimus), and Strattera (atomoxetine).

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  • Humalog® (insulin lispro injection of recombinant DNA origin, Lilly) Humulin® (human insulin of recombinant DNA origin, Lilly) Strattera® (atomoxetine hydrochloride, Lilly)

  • The drugs included in the study were stimulants such as methylphenidate, dextroamphetamines, amphetamine salts and pemoline; and the non-stimulant atomoxetine.

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  • Strattera, or atomoxetine, was approved in May 2008.

  • Lilly's expert testified that if in 1995 he heard the hypothesis that atomoxetine would be effective in treating ADHD, he would have responded: "you're wrong, it's not a good model."

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  • Lilly's expert also explained that a person of ordinary skill in the art "would not predict atomoxetine would be effective" as "we were moving away from single neurotransmitter drugs."

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  • The inventor admitted that treating ADHD with atomoxetine was merely hypothetical.

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