from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any of several
intramolecular interactionsthat regulate proteinfunction
Sorry, no etymologies found.
Vardar-Ulu D, Histen G, Sanchez-Irizarry C, Aster JC, et al. (2007) Structural basis for autoinhibition of Notch.
The two-stage activation pathway and the autoinhibition mechanism, which are probably shared by other members of the
Graves BJ (2000) Phosphorylation represses ETS-1 DNA by reinforcing autoinhibition.
ABL family tyrosine kinases are tightly regulated by autoinhibition and phosphorylation mechanisms.
These findings are consistent with an allosteric kinase activation mechanism by which RIN1 binding promotes a more accessible ABL catalytic site through relief of autoinhibition.