Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A protein found in uncooked egg white that binds to and inactivates biotin. An abundance of avidin in the diet can result in a deficiency of biotin.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biology A tetrameric protein produced in the oviducts of birds, reptiles and amphibians and deposited in the whites of their eggs.

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[avid + (biot)in, from its affinity for biotin.]

Examples

  • Raw eggs Contain an enzyme called avidin, which decreases the absorption of biotin (a B vitamin).

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  • Raw eggs Contain an enzyme called avidin, which decreases the absorption of biotin (a B vitamin).

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  • Endogenous peroxidase and avidin/biotin were blocked using commercial Kits (DAKO).

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  • Briefly, sections were blocked in either normal goat, rabbit or horse serum containing 10% (v/v) from stock avidin solution (Vector Labs) for 20 min followed by 1 hr incubation with anti-PPARβ/δ

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  • Biotin and avidin (or streptavidin) bind non-covalently with a higher binding affinity than most antigen-antibody interactions. 1, 2 This very tight binding makes labeling proteins with biotin a useful tool for applications such as affinity chromatography and immunoanalytical methods.

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  • Boston BioCom has produced HSP-avidin fusion protein for use in a self-assembling vaccines platform as part of collaboration between its Jantibody Therapeutics subsidiary and Pfenex.

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  • Five commercially available antibodies were tested in tissue array sections immunostained utilizing the avidin-biotin (AB) technique.

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  • The collaboration used the Pfenex Expression Technology platform to produce initial amounts of HSP-avidin fusion protein for the Jantibodies self-assembling vaccines platform.

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  • Sections were subsequently developed by avidin-biotin peroxidase complex system following manufacturer's instructions (ABC Kit, Vector Labs).

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  • The entire IN reaction was followed by immunosorbent assay on avidin-coated plates as described previously Fluorescein-labeled peptides at a final concentration of 10 µM in PBS were incubated with HeLa cells for 1 h at 37°C.

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