Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A
human monoclonal antibody that inhibits the biological activity of B-lymphocyte stimulator (BLyS).
Etymologies
Sorry, no etymologies found.
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Examples
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The European Medicines Agency's Committee for Medicinal Products for Human Use, or CHMP, recommended marketing authorization for Benlysta, also known as belimumab.
Glaxo, Human Genome Sciences Win EU Backing for Lupus Drug Sten Stovall 2011
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In draft guidance, the U.K.'s National Institute for Health and Clinical Excellence said, NICE's independent appraisal committee has looked carefully at the evidence provided on the use of belimumab for treating SLE systemic lupus erythematosus, including the views of people with the condition, those who represent them, and clinical specialists.
Lupus Drug Suffers U.K. Setback Sten Stovall 2011
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Whilst recognizing the severity of the disease, the committee concluded that based on this evidence, belimumab could not be considered a good use of NHS resources.
Lupus Drug Suffers U.K. Setback Sten Stovall 2011
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Benlysta, or belimumab, is the first new lupus treatment in 50 years.
Lupus Drug Suffers U.K. Setback Sten Stovall 2011
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The evidence considered did not persuade the committee that belimumab was good value for money, compared to standard care, as the cost per year of improved health is very high.
Lupus Drug Suffers U.K. Setback Sten Stovall 2011
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HGS and GSK are developing belimumab under a definitive co-development and co-commercialization agreement entered into in 2006.
unknown title 2011
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The European summary of product characteristics SmPC lists patient groups which have not been studied with belimumab, including severe active CNS lupus or severe active lupus nephritis.
unknown title 2011
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Caution should be exercised if belimumab is co-administered with other B-cell targeted therapy or cyclophosphamide, as it has not been studied in combination with these agents.
unknown title 2011
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The company originally tested Benlysta, known generically as belimumab, as a treatment for rheumatoid arthritis.
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The company originally tested Benlysta, known generically as belimumab, as a treatment for rheumatoid arthritis.
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