Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
biguanide .
Etymologies
Sorry, no etymologies found.
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Examples
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The oral anti-diabetic agents are categorized in four classes based on the mechanism of action: biguanides (reduced gluconeogenesis) thiazolidinediones (PPAR-g ligands), insulin secretagogues (closure of K+ channels on B cells), and a-glucosidase inhibitors (inhibitors of a-glucosidases).
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It is perceived that a class of anti-diabetic drugs, i.e., biguanides such as Metformin and Phenformin, exert their pharmacological activities via interruption of mitochondrial respiratory electron transport chain; likely via inhibition of Complex I
PLoS ONE Alerts: New Articles Kwangmi Kim et al. 2009
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Yeah, incretins, whether direct or indirect are the new CME hotness with the associated mindshare, but compared to your TZDs, biguanides, and sulfonylureas, they're a distant a second / third / fourth fiddle in volume, if not cost.
OnThePharm RJS 2008
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Two major drug classes that have been in use for some decades are biguanides (metformin) and sulphonylureas (eg: - chlorpropamide, gliclazide and glyburide).
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