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biodistribution

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biology, biochemistry The distribution (static and dynamic) of compounds within a biological system or within an organism

Etymologies

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Examples

  • GLP-compliant repeat-dose toxicology, biodistribution, and genomic integration studies required to position such vaccines for clinical trials were conducted in rabbits and confirmed that a vaccine produced by the RapidResponseTM system was well-tolerated.

    unknown title 2011

  • Confocal microscopy and biodistribution assays were performed to evaluate the localization and uptake of the FITC-conjugated CPE peptide in established tumor tissue.

    BioMed Central - Latest articles 2010

  • [48] Studies include in vitro and in vivo by Western blot analysis, acute biodistribution studies and immunoPET.

    PLoS ONE Alerts: New Articles Jason P. Holland et al. 2010

  • Pre-treatment with PU-H71 was followed by biodistribution studies and immunoPET of

    PLoS ONE Alerts: New Articles 2010

  • Importantly, previous studies in our laboratory using the Focus 120 microPET and "non-saturating" PET radiotracers have demonstrated close agreement between imaging and biodistribution-derived activity concentrations.

    PLoS ONE Alerts: New Articles 2010

  • • Use established in vivo bioimaging machinery to investigate biodistribution of new formulations

    Naturejobs - All Jobs 2010

  • The second presentation described results of a biodistribution comparison of CPX-351 to empty liposomes in a human leukemia xenograft model.

    Nano Tech Wire 2010

  • GMP cell bank production and storage, cell bank and viral vector safety testing, viral clearance services, biodistribution studies, analysis of biofluids using immunochemistry based techniques and extensive protein chemistry support including cGMP batch release and stability testing.

    Naturejobs - All Jobs 2010

  • Yuan Y, Xu F, Tao X, et al. (2009) In vitro macrophage uptake and in vivo biodistribution of long-circulation nanoparticles with poly (ethylene-glycol) - modified PLA (BAB type) triblock copolymer.

    PLoS ONE Alerts: New Articles Hans-Christian Ingerslev et al. 2010

  • "Using quantum dots as a model system, we have systematically defined the physicochemical parameters that mediate uptake of nanoparticles by the lung, their biodistribution to tissues, organs and tumors and their clearance from the body," said Frangioni.

    Nano Tech Wire 2010

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