Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adverb With regard to
bioenergetics
Etymologies
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Examples
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If direct phosphorylation is sufficient to induce Parkin recruitment to mitochondria, however, it seems difficult to explain how Parkin can be targeted to a particular subset of mitochondria, as appears to occur in cells with bioenergetically diverse populations of mitochondria
PLoS Biology: New Articles Derek P. Narendra et al. 2010
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Although PINK1-YFP colocalizes with cytochrome c, which is present in all mitochondria (average Pearson coefficient = 0. 58±0.11), PINK1-YFP does not colocalize with MTR (average Pearson coefficient = 0. 26±0.13), which accumulates only in bioenergetically active mitochondria (t-test).
PLoS Biology: New Articles Derek P. Narendra et al. 2010
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In this model, mitochondrial PINK1 is rapidly turned over on bioenergetically well-coupled mitochondria by proteolysis, but is selectively stabilized on mitochondria with low membrane potential.
PLoS Biology: New Articles Derek P. Narendra et al. 2010
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We found that, similar to YFP-Parkin [21], PINK1-YFP accumulates selectively on mitochondria with low membrane potential, demonstrating that PINK1 is selectively stabilized on the depolarized mitochondria within a bioenergetically diverse population of mitochondria (
PLoS Biology: New Articles Derek P. Narendra et al. 2010
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