Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry The attachment of a biotin residue to a biological macromolecule in order to label it.

Etymologies

Sorry, no etymologies found.

Support

Help support Wordnik (and make this page ad-free) by adopting the word biotinylation.

Examples

  • (B) Surface biotinylation of Cav1. 2 in these primary cardiomyocytes indicates a 45% reduction of surface Cav1. 2 after BIN1 knockdown.

    PLoS Biology: New Articles Ting-Ting Hong et al. 2010

  • Surface biotinylation of endogenous Cav1. 2 in cultured HL-1 cells.

    PLoS Biology: New Articles Ting-Ting Hong et al. 2010

  • The first committed step in lipid biosynthesis is the biotinylation of Acetyl Coenzyme A Carboxylase (ACC) mediated by biotin acetyl-CoA carboxylase ligase/biotin protein ligase (BirA) [3] - [5]

    PLoS ONE Alerts: New Articles Vibha Gupta et al. 2010

  • The SensoLyte® Biotin Quantitation Assay Kit provides a convenient way to estimate the efficiency of biotinylation for biotin-protein conjugates.

    PR.com Press Releases Inc. AnaSpec 2010

  • Chapman-Smith A, Cronan JE Jr (1999) The enzymatic biotinylation of proteins: a post-translational modification of exceptional specificity.

    PLoS ONE Alerts: New Articles Vibha Gupta et al. 2010

  • Chapman-Smith A, Cronan JE Jr (1999) The enzymatic biotinylation of proteins: a post-translational modification of exceptional specificity.

    PLoS ONE Alerts: New Articles Vibha Gupta et al. 2010

  • Involvement of these mobile loops in the biotinylation reaction is indispensable and hence the knowledge of their structure is critical for new leads into protein-ligand interactions.

    PLoS ONE Alerts: New Articles Vibha Gupta et al. 2010

  • Involvement of these mobile loops in the biotinylation reaction is indispensable and hence the knowledge of their structure is critical for new leads into protein-ligand interactions.

    PLoS ONE Alerts: New Articles Vibha Gupta et al. 2010

  • The first committed step in lipid biosynthesis is the biotinylation of Acetyl Coenzyme A Carboxylase (ACC) mediated by biotin acetyl-CoA carboxylase ligase/biotin protein ligase (BirA) [3] - [5]

    PLoS ONE Alerts: New Articles Vibha Gupta et al. 2010

  • Reaction conditions for biotinylation are chosen such that the target molecule (e.g. an antibody) is labeled with sufficient biotin residues to purify or detect the molecule, but not too much that the biotin will interfere with the function of the molecule.

    PR.com Press Releases Inc. AnaSpec 2010

Comments

Log in or sign up to get involved in the conversation. It's quick and easy.