Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry The attachment of a biotin residue to a biological macromolecule in order to label it.

Etymologies

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Examples

  • (B) Surface biotinylation of Cav1. 2 in these primary cardiomyocytes indicates a 45% reduction of surface Cav1. 2 after BIN1 knockdown.

    PLoS Biology: New Articles

  • Surface biotinylation of endogenous Cav1. 2 in cultured HL-1 cells.

    PLoS Biology: New Articles

  • The first committed step in lipid biosynthesis is the biotinylation of Acetyl Coenzyme A Carboxylase (ACC) mediated by biotin acetyl-CoA carboxylase ligase/biotin protein ligase (BirA) [3] - [5]

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  • The SensoLyte® Biotin Quantitation Assay Kit provides a convenient way to estimate the efficiency of biotinylation for biotin-protein conjugates.

    PR.com Press Releases

  • Chapman-Smith A, Cronan JE Jr (1999) The enzymatic biotinylation of proteins: a post-translational modification of exceptional specificity.

    PLoS ONE Alerts: New Articles

  • Chapman-Smith A, Cronan JE Jr (1999) The enzymatic biotinylation of proteins: a post-translational modification of exceptional specificity.

    PLoS ONE Alerts: New Articles

  • Involvement of these mobile loops in the biotinylation reaction is indispensable and hence the knowledge of their structure is critical for new leads into protein-ligand interactions.

    PLoS ONE Alerts: New Articles

  • Involvement of these mobile loops in the biotinylation reaction is indispensable and hence the knowledge of their structure is critical for new leads into protein-ligand interactions.

    PLoS ONE Alerts: New Articles

  • The first committed step in lipid biosynthesis is the biotinylation of Acetyl Coenzyme A Carboxylase (ACC) mediated by biotin acetyl-CoA carboxylase ligase/biotin protein ligase (BirA) [3] - [5]

    PLoS ONE Alerts: New Articles

  • Reaction conditions for biotinylation are chosen such that the target molecule (e.g. an antibody) is labeled with sufficient biotin residues to purify or detect the molecule, but not too much that the biotin will interfere with the function of the molecule.

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