Definitions
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Etymologies
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Examples
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The brain and spinal cord are insulated by a tight cellular seal called the blood-brain barrier that prevents foreign chemicals from easily getting into the brain.
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The entire neurological system is protected by something called the blood-brain barrier, a set of tightly packed cells that acts as kind of a filter system, protecting the brain.
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The brain is walled off from the microbiome by a series of biochemical moats and ramparts known as the blood-brain barrier.
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One advantage of IGF-II is that it can cross the blood-brain barrier, so it could potentially be administered through the bloodstream or as a vapor through the nose, rather than injected directly into the brain.
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Current treatments can relieve many symptoms, but not the neurological effects, because the therapies can't cross the blood-brain barrier, according to the companies.
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"The drug comes in and it's soaked up, and you try to soak up as much as you can before it crosses the blood-brain barrier."
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Although the drug is easily absorbed when taken orally, the body's blood-brain barrier protects it from getting to its target — the spinal cord area.
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The key is getting the drugs on site, rather than having them circulate through the body only to be stymied by the blood-brain barrier.
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The partnership represents Medtronic's latest attempt to get medication past the blood-brain barrier, a tightly packed network of cells in brain capillaries that only lets certain substances through, including key nutrients.
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The pact, announced Tuesday, adds to Medtronic's roster of projects aimed at using implantable drug pumps and catheters to circumvent the blood-brain barrier.
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