Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A dual endothelin receptor antagonist important in the treatment of pulmonary artery hypertension.
Etymologies
Sorry, no etymologies found.
Examples
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They did a research, I know, in Mayo on a drug called, I think it's called bosentan, Tracleer bosentan.
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Pulmonary vasodilator therapy for pulmonary hypertension, including new agents such as bosentan (Tracleer) and sildenafil (Viagra)
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The Swiss drug maker said a clinical study of bosentan to treat idiopathic pulmonary fibrosis didn't meet its primary endpoint of reducing morbidity and mortality.
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Candidates for ranging from bosentan at around botox liver.
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Coadministration with the following is not recommended: nevirapine or salmeterol; other protease inhibitors, fluticasone propionate, or voriconazole when REYATAZ ® atazanavir sulfate is given with ritonavir; buprenorphine or bosentan when REYATAZ is given without ritonavir; proton-pump inhibitors or efavirenz in treatment-experienced patients; and colchicine in patients with renal or hepatic impairment.
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The study was supported by Actelion Pharmaceuticals, the manufacturer of bosentan.
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Explain to interested patients that the drug bosentan, which can help improve some features of systemic sclerosis such as pulmonary arterial hypertension, did not increase exercise capacity in a randomized trial.
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Pulmonary hypertension developed in five patients on placebo and in one patient on bosentan.
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Adverse events including skin ulcers, fatigue, peripheral edema, and elevated liver enzymes were seen in more than 10% of patients in the bosentan arm.
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Pulmonary function remained stable in most patients in both groups, at 69% in the bosentan group and 60.3% of the placebo patients.
Comments
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