from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A poisonous hallucinogenic alkaloid, C12H16N2O, obtained from the skin glands of toads of the genus Bufo or from some mushrooms.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An alkaloid, found in the skins of some toads, related to serotonin.


French bufoténine : Latin būfō, toad + probably Latin tenēre, to hold (because of its paralyzing effect); see ten- in Indo-European roots + French -ine, -ine; see -ine2.
(American Heritage® Dictionary of the English Language, Fourth Edition)


  • The problem is that the glands of the toad secrete another chemical known as bufotenine, a compound that is found in a hallucinogenic snuff made from a plant by Indians of the upper Orinoco in Venezuela.

    The Serpent and the Rainbow

  • The toad's venom — which is secreted when the toad gets angry or scared — contains a hallucinogen called bufotenine that can be dried and smoked to produce a buzz.

    When Toads are Outlawed . . .

  • Further experiments led this audacious physician to conclude that the symptoms produced by bufotenine coincided curiously with the conditions of the berserkus of Norse legend.

    The Serpent and the Rainbow

  • But even if it had, it seems that bufotenine alone would be enough to ruin any experience.

    The Serpent and the Rainbow

  • In the late 1950s Howard Fabing, a medical doctor, obtained permission to inject bufotenine intravenously into a number of inmates at the Ohio State Penitentiary.

    The Serpent and the Rainbow

  • S., Intravenous bufotenine injection in the human being, Science 123 1956: 886-87; Flier, J., M.

    The Serpent and the Rainbow

  • Dimethyltryptamine, bufotenine, mescaline, and lysergic acid amide are mentioned by name in these statutes, stories: News


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