Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A potent, long-acting anesthetic, C18H28N2, used for regional anesthesia in its hydrochloride form.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A local anesthetic drug of the amino amide group.

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[bu(tyl) + pi(peridine) + (no)vacaine (popular rendering of the trademark Novocain, influenced by cocaine).]

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Examples

  • For that, we use a combination of a local anesthetic called bupivacaine, some opiate medication called fentanyl, and morphine, and that gives you analgesia for almost 24 to 48 hours after the C-section so that you don't require any form of IV pain relief.

    All MayoClinic.com Topics 2008

  • ELADUR is a transdermal patch containing bupivacaine, which is designed to provide up to three days of pain relief versus the existing market-leading patch, which is indicated for 12 hours of wear.

    Healthcare Sector and Stocks Analysis from Seeking Alpha 2008

  • Ganesh A, Adzick NS, Foster T, Cucchiaro G. Efficacy of addition of fentanyl to epidural bupivacaine on postoperative analgesia after thoracotomy for lung resection in infants.

    Congenital cystic adenomatoid malformation publications 2010

  • Most anesthetic drug names end with the suffix “-caine,” such as lidocaine and bupivacaine.

    Pregnancy, Childbirth, and the Newborn Penny Simkin 2010

  • Most anesthetic drug names end with the suffix “-caine,” such as lidocaine and bupivacaine.

    Pregnancy, Childbirth, and the Newborn Penny Simkin 2010

  • PCRX's clinical data demonstrates that EXPAREL provides analgesia for up to 72 hours post-surgery, compared with seven hours or less for bupivacaine.

    unknown title 2011

  • Business -- Has filed a New Drug Application, or NDA, for the lead product candidate, EXPAREL, a long-acting bupivacaine anesthetic/analgesic product for postsurgical pain management.

    unknown title 2011

  • Less pain over 72 hours was demonstrated for patients receiving EXPAREL compared to patients receiving bupivacaine HCl, as evidenced by an area under the curve analysis, a measure of pain over time AUC0-72 315 vs 427, respectively.

    unknown title 2011

  • In this study, 107 patients were randomly assigned to one of three treatment groups prior to undergoing elective arthroscopic shoulder surgery: POSIDUR at a dose of 5 mL, an active comparator (commercially available bupivacaine HCI solution) or SABER-Placebo (SABER vehicle without drug).

    unknown title 2011

  • It is intended to be administered during surgery, where it continuously releases therapeutic levels of bupivacaine in a controlled fashion, providing up to 72 hours of uninterrupted local analgesia.

    unknown title 2011

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