c-Fos

They established this by measuring the amount of c-Fos in the area, a biochemical marker whose presence indicates that serotonin releasing neurons have fired.

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Most of the genes encoding inflammatory cytokines and matrix-degrading MMPs are under the control of c-Fos/AP-1, and it plays a very important role in the destruction of arthritic joints

PLoS ONE Alerts: New Articles Gang Wu et al. 2010

Accordingly, in import assays in vitro, primary cells showed a lower import activity for ERK1/2 than cancer cells, in which activated MAPK readily translocated into the nucleus and activated c-Fos expression.

Elites TV PLoS ONE 2010

Further, it increased c-Fos expression in this region, suggesting blockade of tonic inhibition and thus the disinhibition of local neurons.

BioMed Central - Latest articles 2010

This manipulation also increased c-Fos expression in structures including the ventral tegmental area, medial shell of the nucleus accumbens, medial prefrontal cortex, septal area, preoptic area, lateral hypothalamic area and dorsal raphe nucleus.

BioMed Central - Latest articles 2010

Here, however, we observe that in primary cultures of breast and ovarian epithelial cells, phosphorylation and activation of ERK1/2 are disassociated from nuclear translocalization and transcription of downstream targets, such as c-Fos, suggesting that nuclear translocation is limited in primary cells.

Elites TV PLoS ONE 2010

Taken together, our findings indicate that Trolox prevents osteoclast formation and bone loss by inhibiting both RANKL induction in osteoblasts and c-Fos expression in

Journal of Biological Chemistry current issue 2009

Moreover, mitogen and stress-activated kinase 1 / 2 (MSK1 / 2) double knockout mice showed highly impaired immobility behavior in the re-test of the forced swim test in conjunction with virtually absent histone H3 phospho-acetylation and c-Fos responses to forced swimming in the dentate gyrus; elsewhere in the brain (including the nucleus accumbens) c-Fos responses to forced swimming were normal

PLoS ONE Alerts: New Articles Andrew Collins et al. 2009

Forced swimming induced a marked increase in the number of c-Fos

PLoS ONE Alerts: New Articles Andrew Collins et al. 2009

Taken together, our findings indicate that Trolox prevents osteoclast formation and bone loss by inhibiting both RANKL induction in osteoblasts and c-Fos expression in

Journal of Biological Chemistry current issue J.-H. Lee 2009