from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The polypeptide hormone cachexin or tumor necrosis factor


Sorry, no etymologies found.


  • Gerlach H, Nawroth P, Steinberg S, Godman G, et al. (1989) Tumor necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins.

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  • Tumor necrosis factor (TNF, cachexin or cachectin and formally known as tumor necrosis factor-alpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction.

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  • Burchett SK, Weaver WM, Westall JA, Larsen A, Kronheim S, et al. (1988) Regulation of tumor necrosis factor/cachectin and IL-1 secretion in human mononuclear phagocytes.

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