Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun Any of a class of enediyne antibiotics derived from the bacterium Micromonospora echinospora, extremely toxic to all living cells and used in targeted therapy against cancer.

Etymologies

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Examples

  • According to the study, calicheamicin, a secondary metabolite of Micromonospora echinospora, is what gave the river its toxic reputation.

    The Times of India 2010

  • The researchers believe this mythic poison must be calicheamicin.

    The Times of India 2010

  • The biosynthesis of the enediyne moiety of the antitumor natural product calicheamicin involves an iterative polyketide synthase

    Journal of Biological Chemistry current issue M. Kotaka 2009

  • Cells were exposed either to the radiomimetic drug calicheamicin γ1 (CLγ1) or to ionizing radiation (IR) to create DSBs.

    PLoS ONE Alerts: New Articles 2008

  • Cells were exposed either to the radiomimetic drug calicheamicin γ1 (CLγ1) or to ionizing radiation (IR) to create DSBs.

    PLoS ONE Alerts: New Articles Aline Meulle et al. 2008

  • Alexander the Great © Clipart. com Scientists think it may have been caused by calicheamicin, a compound formed from poisonous bacteria from a stream (Mavroneri or

    About.com Ancient / Classical History 2010

  • Mylotarg®), a drug that is used to treat acute myelogenous leukemia (AML), consists of an antibody connected to calicheamicin, a highly toxic antibiotic.

    Health News from Medical News Today 2009

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