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- n. Any of a family of proteins that binds calcium
Sorry, no etymologies found.
Many actin-binding proteins contain calponin homology (CH) domains, but the manner in which these domains interact with F-actin has been controversial.
H2-calponin-free macrophages demonstrated a higher rate of proliferation and faster migration than that of h2-calponin-positive cells, consistent with a faster diapedesis of peripheral monocytes and neutrophils.
H2-calponin-free mice showed reduced numbers of peripheral blood neutrophils and monocytes.
Here we report the finding of significant levels of the h2 isoform of calponin in peripheral blood cells of myeloid lineage.
H2-calponin-free macrophages showed reduced spreading in adhesion culture together with decreased tropomyosin in the actin cytoskeleton.