Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun The state or condition of being
cardiotoxic .
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
Support
Help support Wordnik (and make this page ad-free) by adopting the word cardiotoxicity.
Examples
-
July 2010 after the PDCO recommended CTI expand the original PIP to include pixantrone's potential clinical benefit of reducing long-term cardiotoxicity associated with current curative therapies in children.
-
"Some may conclude that establishing this hurdle of long, costly trials for drugs that have no suggestion of cardiotoxicity will stifle drug development for Type 2 diabetes," the FDA said.
-
Antidepressants that have less cardiotoxicity and fewer anticholinergic side effects are preferable desipramine, nortriptyline, fluoxetine.
The Neuropsychiatric Guide to Modern Everyday Psychiatry Michael Alan Taylor 1993
-
Herceptin is also associated with cardiotoxicity due to previous treatment with doxorubicin; this is also expected to be eliminated with the use of the T-DM1 conjugate.
Roche Scores Big With Plexxikon and Immunogen Deals - Seeking Alpha 2011
-
Roche says that it is already running screens based on stem cells to test drugs for cardiotoxicity and effects on neurogenesis.
Scientific American 2010
-
Their usage has been hampered by side effects, particularly, cardiotoxicity.
-
His group was one of the first to report that survivors of childhood cancer faced not only acute cardiotoxicity from treatment, but also late cardiac effects.
MedPageToday.com - medical news plus CME for physicians 2010
-
These novel pharmacologic differences may allow re-introduction of anthracycline like potency in the treatment of relapsed/refractory aggressive lymphoma without unacceptable rates of cardiotoxicity.
-
These novel pharmacologic differences may allow re-introduction of anthracycline like potency in the treatment of relapsed/refractory aggressive lymphoma without unacceptable rates of cardiotoxicity.
-
In addition, the structural motifs on anthracycline-like agents that are responsible for the generation of oxygen free radicals and the formation of toxic drug-metal complexes have also been modified in pixantrone to prevent the binding of iron and perpetuation of superoxide production -- both of which are the putative mechanism for anthracycline induced acute cardiotoxicity.
Comments
Log in or sign up to get involved in the conversation. It's quick and easy.