Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of caveola.

Etymologies

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Examples

  • You will study the direct effects of statins on the cardiac myocyte - through cholesterol-dependent (caveolae) and independent (isoprenoid) pathways.

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  • Trigatti B, Rigotti A, Smart EJ, Anderson RG, et al. (1997) Murine SR-BI, a high density lipoprotein receptor that mediates selective lipid uptake, is N-glycosylated and fatty acylated and colocalizes with plasma membrane caveolae.

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  • We show that caveolin 1, the structural protein component of caveolae, is a TrxR1-binding protein by demonstrating that the scaffolding domain of caveolin 1 (amino acids 82-101) binds directly to the caveolin-binding motif (CBM) of TrxR1

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  • A TrxR1 mutant lacking the CBM, which fails to localize to caveolae and bind to caveolin 1, is constitutively active and inhibits oxidative-stress-mediated activation of the p53/p21

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  • Boucher P, Liu P, Gotthardt M, Hiesberger T, Anderson RG, et al. (2002) Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae.

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  • We have earlier shown that the binding and assembly of α-HL requires functional form of Caveolin-1 which is an integral part of caveolae.

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  • C internalization requires activated Cdc-42 and is sensitive to cholesterol depletion but not to cav-1 expression suggesting a role for rafts but not for caveolae in PrP

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  • Clathrin and caveolae internalization pathways were monitored through specific inhibitors monodansylcadaverine (MDC) and methyl-beta-cyclodextrin (MBCD), respectively.

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  • Cell-surface viral proteins most frequently enter the cell through clathrin or caveolae endocytosis.

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  • However, under pathological conditions, both aggregated Aβ and α-syn might associate with membranes and accumulate in caveolae

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