Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Of or pertaining to the caveolae

Etymologies

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Examples

  • This nano-shuttle system is believed to activate an albumin-specific (Gp60) receptor-mediated transcytosis path through the cell wall of proliferating tumor cells, using caveolin-1 activated caveolar transport.

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  • By using a proteomic-based approach, here we identify TrxR1 as a caveolar membrane-resident protein.

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  • As it has been shown that the internalization of clathrin-coated vesicles and the uptake of caveolar microdomains are dependent on the functionality of the large GTPase dynamin we additionally analyzed the impact of dynamin for HPV16 entry and infection.

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  • Multiple forms of endocytosis, including both clathrin and caveolar mediated endocytosis, require dynamin GTPase activity for vesicle formation at the cell surface.

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  • Cholera toxin subunit B (CtxB), which enters cells mainly by a caveolar-mediated entry route when applied at low concentrations, was used as a marker

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  • For HPV16, it was reported that entry occurs by clathrin-mediated endocytosis, whereas HPV31 was shown to use caveolar-mediated uptake mechanisms In the present study we have readdressed the early mechanisms of HPV16 invasion into host cells following binding to HSPGs.

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  • (Cav-GFP) that was shown to function as a marker for caveolae, and an N-terminally tagged version (GFP-Cav) that acts as dominant negative mutant inhibiting caveolar-mediated endocytosis

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  • Viral uptake often takes place via clathrin - or caveolar / raft-mediated endocytosis.

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  • Kirkham M, Parton RG (2005) Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers.

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  • These observations demonstrate that internalization of extracellular rPrP occurs through a lipid raft-dependent process that is independent of both caveolar - and clathrin-mediated endocytosis.

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