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Examples

  • The insulin receptor is the cell-surface molecule to which the hormone insulin binds.

    Ora Mendelsohn Rosen. 2009

  • Pancreatic β cell-surface expression of glucose transporter 2 Glut-2 is essential for glucose-stimulated insulin secretion, thereby controlling blood glucose homeostasis in response to dietary intake.

    “I have vision, and the rest of the world wears bifocals.”* | The Blog of Michael R. Eades, M.D. 2006

  • Loss of GlcNAcT-IVa, or the addition of glycan-ligand mimetics, attenuates Glut-2 cell-surface half-life, provoking endocytosis with redistribution into endosomes and lysosomes.

    “I have vision, and the rest of the world wears bifocals.”* | The Blog of Michael R. Eades, M.D. 2006

  • The Ig superfamily is involved in cell-to cell adhesion and cell-surface adhesion.

    Stuck on you, biological Velcro and the evolution of adaptive immunity - The Panda's Thumb 2006

  • To recap, Phenotype As have genes that prime them for addiction and overeating or bingeing—either by leading to deficient neurotransmitters or deficient cell-surface receptors for neurotransmitters.

    Fat is Not Your Fate Susan Mitchell Ph.D. 2005

  • To recap, Phenotype As have genes that prime them for addiction and overeating or bingeing—either by leading to deficient neurotransmitters or deficient cell-surface receptors for neurotransmitters.

    Fat is Not Your Fate Susan Mitchell Ph.D. 2005

  • Thomas Andersson, CEO LU Bio, thomas@lubio.se, telephone +46 70 287 00 15 Agneta Svedberg, CEO Cantargia, agneta.svedberg@cantargia.com, +46 0 705 14 11 63 Cantargia is developing a conceptually new cancer therapy, based on the original discovery that certain leukemia stem cells express a specific cell-surface receptor, whereas corresponding normal hematopoietic stem cells do not express this receptor.

    Reuters: Press Release 2012

  • Alemtuzumab is a humanized monoclonal antibody being studied as a potential therapy for relapsing MS. Alemtuzumab targets the cell-surface glycoprotein CD52, which is highly expressed on T- and B-lymphocytes.

    unknown title 2011

  • The protein interacts with many cell-surface receptors including those involved in bone growth, inflammation and wound healing.

    eHow - Health How To's 2010

  • In addition to Trubion's current clinical stage product pipeline, the Company is also developing its multi-specific SCORPION technology, both for targeting cell-surface molecules like CD79b and HLA-DR, as well simultaneously neutralizing soluble ligands like TNF and IL-6.

    Medindia Health News 2010

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