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chemosensitization

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun medicine treatment of a tumour with a medication in order to make it more susceptible to radiation treatment

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

chemo- +‎ sensitization

Examples

  • The sensitization effect of certain substances with regard to other chemicals - referred to as the chemosensitization effect by scientists - does not play a role in the current legislation.

    innovations-report

  • The CK2 protein expression levels were determined and the effect of its down-regulation on chemosensitization of pancreatic cancer cells was investigated.

    BioMed Central - Latest articles

  • Our results demonstrate that in p53-deficient human gastric cancer cells, restoration of functional miR-34 inhibits cell growth and induces chemosensitization and apoptosis, indicating that miR-34 may restore p53 function.

    BioMed Central - Latest articles

  • Finally, our studies suggest a molecular link between the inhibition of GRP78 / BIP and E2F1-mediated chemosensitization of tumor cells, underscoring its relevance for cancer treatment.

    Journal of Biological Chemistry current issue

  • Interestingly, AGS KD cells transfected with si p53 were significantly less susceptible to growth inhibition by 5-FU than AGS KD cells transfected with control siRNA (siRNA silencing of p53 reverses the chemosensitization of AGS KD cells.

    PLoS ONE Alerts: New Articles

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