from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A particular
drugused in chemotherapy.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun an alkalating agent (trade name Leukeran) used to treat some kinds of cancer
Sorry, no etymologies found.
Professor Hillmen, who is lead investigator for the CLL208 trial, explained: "Rituximab's capabilities in combination with FC chemotherapy have been well proven, however this trial examined its interaction with chlorambucil, which is the standard treatment prescribed for frailer patients with CLL.
The interim results from this study indicate that adding rituximab to this commonly used chemotherapy improves the overall response rate by 17.3 per cent compared to historical data from patients in another UK study (CLL4) who received chlorambucil alone.
In a separate UK-only study, CLL208, also presented at ASH, rituximab was trialled in combination with chlorambucil chemotherapy in previously untreated CLL patients.
Patients were treated with one of the following first-line chemotherapy regimens: chlorambucil, fludarabine, fludarabine-containing regimen, CVP/COP, CHOP, CHOP-like, or rituximab-containing chemotherapy.
Genzyme Corp. and Berlex Inc. have announced results from CAM307, an international Phase III clinical trial comparing Campath (alemtuzumab) with chlorambucil in previously untreated patients with B-cell chronic lymphocytic leukemia.
Alemtuzumab is superior to chlorambucil as first-line treatment for patients with chronic lymphocytic leukemia (CLL), according to results of a study published in the December issue of the Journal of Clinical Oncology.
There are currently no FDA approved drugs for Waldenstrom's, with nucleoside analogues, the proteasome inhibitor bortezomib (Velcade (R)), alkylating agents (chlorambucil) and rituximab (Rituxan (R)) often used to treat the disease.