from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A chronic disease of the liver characterized by the replacement of normal tissue with fibrous tissue and the loss of functional liver cells. It can result from alcohol abuse, nutritional deprivation, or infection especially by the hepatitis virus.
  • n. Chronic interstitial inflammation of any tissue or organ.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A chronic disease of the liver caused by damage from toxins (including alcohol), metabolic problems, hepatitis or nutritional deprivation. It is characterised by an increase of fibrous tissue and the destruction of liver cells.
  • n. Interstitial inflammation of kidneys, lungs, and other organs.

from the GNU version of the Collaborative International Dictionary of English

  • n. A disease of the liver in which it usually becomes smaller in size and more dense and fibrous in consistence; hence sometimes applied to similar changes in other organs, caused by increase in the fibrous framework and decrease in the proper substance of the organ.

from The Century Dictionary and Cyclopedia

  • n. In pathology, chronic inflammation of interstitial connective tissue, especially of the liver.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. a chronic disease interfering with the normal functioning of the liver; the major cause is chronic alcoholism


New Latin : Greek kirros, tawny (from the color of the diseased liver) + -osis.
(American Heritage® Dictionary of the English Language, Fourth Edition)
From Ancient Greek κιρρός (kirrhos, "tawny") and -osis (Wiktionary)



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