Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry A fibrous protein that forms a polyhedral coat on the surface of the coated pits and vesicles of cells during endocytosis

Etymologies

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Examples

  • The vesicles also appeared to include a coat made from a molecule called clathrin, which helps form the outer shell of the vesicles.

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  • Interestingly, swiggle-mediated inhibition of MT1-MMP clathrin-mediated internalisation was also found to promote MT1-MMP-mediated cell migration.

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  • Since transferrin (Tf) is internalized mainly via clathrin-dependent endocytosis, we tested whether the extent of Tf uptake was affected upon treatment of HeLa cells with StxB.

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  • Electron microscopy was used to quantify the number of clathrin-coated pits per mm of plasma membrane before and after incubating cells with Stx for 10 min at 37°C.

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  • This anterograde transport is usually counterbalanced by the retrograde transport of membranes from the plasma membrane to endosomes and the Golgi apparatus via AP-clathrin-coated vesicles, and from the Golgi apparatus back to the ER via COPI-coated vesicles.

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  • Chen Y, Deng L, Maeno-Hikichi Y, Lai M, Chang S, et al. (2003) Formation of an endophilin-Ca2+ channel complex is critical for clathrin-mediated synaptic vesicle endocytosis.

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  • MMP-2 active form then interact with the integrine αvβ3 and is internalized in clathrin-coated vesicle.

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  • Interestingly, swiggle-mediated inhibition of MT1-MMP clathrin-mediated internalisation was also found to promote MT1-MMP-mediated cell migration.

    BioMed Central - Latest articles

  • Activated MMP-2 containing only 7 disulfide bonds is then internalized in clathrin-coated vesicles and subsequently by an unknown mechanism reachs the cytosol for proteasome degradation.

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  • II (COPII) coated vesicles to the Golgi apparatus, and from the Golgi apparatus via adaptor protein (AP) - clathrin-coated vesicles to the plasma membrane.

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