Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry Any of a family of proteins that control the flow of molecules through the epithelium

Etymologies

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Examples

  • Expression of claudin 4, claudin 18, and occludin was significantly lower, and activation of JNK and ERK signaling pathways was significantly increased in 2CLP monolayers, relative to sham monolayers.

    Elites TV 2010

  • Inhibition of ERK, not JNK, significantly increased TER and expression of claudin 4 in 2CLP monolayers, and prevented significant differences in claudin 18 expression between 2CLP and sham monolayers.

    Elites TV 2010

  • Karanjawala ZE, Illei PB, Ashfaq R, Infante JR, Murphy K, et al. (2008) New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8.

    PLoS Medicine: New Articles Jeran K. Stratford et al. 2010

  • RNA from FFPE samples was extracted using two different methods, Ambion and Agencourt, and its quality was determined by profiling starting total RNA on Bioanalyzer and by amplifying increasing size fragments of beta actin (ACTB) and claudin 3 (CLDN3) by reverse-transcriptase polymerase chain reaction.

    BioMed Central - Latest articles 2009

  • For example, iodine-125 radiolabeled anti-claudin-4 antibody has been employed for imaging pancreatic cancer using gamma scintigraphy and single-photon emission computed tomography / computed tomography

    PLoS Medicine: New Articles 2009

  • Foss CA, Fox JJ, Feldmann G, Maitra A, Iacobuzio-Donohue C, et al. (2007) Radiolabeled anti-claudin 4 and anti-prostate stem cell antigen: Initial imaging in experimental models of pancreatic cancer.

    PLoS Medicine: New Articles 2009

  • RNA from FFPE samples was extracted using two different methods, Ambion and Agencourt, and its quality was determined by profiling starting total RNA on Bioanalyzer and by amplifying increasing size fragments of beta actin (ACTB) and claudin 3 (CLDN3) by reverse-transcriptase polymerase chain reaction.

    BioMed Central - Latest articles Steve Guerrero Grazyna Fedorowicz 2009

  • Turksen K, Troy TC (2002) Permeability barrier dysfunction in transgenic mice overexpressing claudin 6.

    PLoS ONE Alerts: New Articles Tammy-Claire Troy et al. 2009

  • The single-letter variation (SNP) occurs in the gene encoding claudin 14 (CLDN14), a protein expressed in the kidney, according to a news release.

    Medlogs - Recent stories 2009

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