from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun medicine The
formationof a cleft lipor cleft palate.
from Wiktionary, Creative Commons Attribution/Share-Alike License
Oral clefting occurs when the tissues of the lip or palate of a foetus do not grow together early in pregnancy, and is a relatively common birth defect.
Of course, the Japanese culture and language evolved together, through one another, as languages always do, and so if you have any familiarity with Japanese culture you may be note that this "clefting" structure is common mostly due to cultural factors.
A clefting abnormality in vertebrae (small bones that make up the spine) that gives them a "flying butterfly" appearance on X-rays.
Disruption of the Hh-signaling pathway in humans can lead to the spectral disorder of Holoprosencephaly (HPE), which is often characterized by a variety of craniofacial defects including midline facial clefting and cyclopia [1,2].
More than half a million children are born each year with craniofacial and clefting abnormalities, but only a "lucky few" receive long-term excellent care until they are fully grown, according to Dr. Salyer.
"This helps to connect some of the developmental dots in the clefting process, and that's powerful information to when designing possible interventions to prevent a cleft."
The discovery marked a potentially important lead because about 15 percent of people with VWS have malformations that are clinically indistinguishable from isolated cleft lip and / or palate, suggesting the gene might be involved in both types of clefting.