clinical-trial

Bayer AG shares slid more than 5% Thursday after better-than-expected clinical-trial data on a rival drug for preventing strokes spooked investors about the prospects of the German group's key medicine Xarelto.

Rival Drug Success Pressures Bayer Sten Stovall 2011

Merck & Co . said Monday that it plans to apply this year for U.S. regulatory approval to market a potential new treatment for insomnia, based on positive clinical-trial results.

Merck to File Insomnia Drug Application Peter Loftus 2012

Dr. McAfee said the discrepancy between clinical-trial and population-survey results might result from so-called selection bias, in which smokers who have a more difficult time quitting are more likely to turn to medication.

Quit Smoking: A New Case for Going Cold Turkey Mike Esterl 2012

ZURICH— Novartis AG said Tuesday it will file its Afinitor drug for world-wide regulatory approval in breast cancer by year end on strong clinical-trial data, raising prospects the product will become a blockbuster and help the Swiss giant offset sales lost from drug-patent expirations.

Novartis Drug Seeks Wider Use Goran Mijuk 2011

Lilly and Amylin submitted Bydureon for FDA approval in May 2009, based on clinical-trial data showing it improved measures of blood sugar versus Byetta.

FDA Approves Amylin's Bydureon Diabetes Drug Peter Loftus 2012

Journal Community The totality of the available biologic, observational and clinical-trial evidence strongly supports the selective use of statin therapy in adults demonstrated to be at high risk for heart disease.

Should Healthy People Take Cholesterol Drugs to Prevent Heart Disease? 2012

Jesse Neider for The Wall Street Journal Richard Kaminski kept a binder to record his progress as a clinical-trial participant for Roche's skin-cancer drug, approved Wednesday by the FDA.

Guided By Genes, Shrinking Cancer Jonathan D. Rockoff 2011

Lundbeck published only a brief summary of the results in a press release Wednesday and didn't release the full set of clinical-trial data, saying it planned to publish the data in a medical journal at a later date.

Danish Alcoholism Drug Does Well in Three Clinical Trials Jeanne Whalen 2011

The U.S. Food and Drug Administration's decision to fast-track Alpharadin follows recent clinical-trial data showing the drug improved overall survival in patients with castration-resistant prostate cancer and symptomatic bone metastases.

Bayer Prostate Drug Gets a Boost Sten Stovall 2011

Mr. White sees the focus of health-care-fraud cases expanding to allegations of manufacturing problems and the submission of false clinical-trial data to secure regulatory approval for new drugs.

Whistleblower's Long Journey Peter Loftus 2010