Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun chemistry Any salt or ester of clodronic acid
  • noun medicine The sodium salt of clodronic acid, used as a bone resorption inhibitor and antihypercalcemic agent

Etymologies

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Examples

  • The drugs, called clodronate and etidronate, steal the DNA binding site, preventing relaxase from handling DNA.

    New Way to Kill Antibiotic-Resistant Bacteria Found | Impact Lab 2007

  • In this work, we demonstrated the efficacy of a new class of non-N-BPs which exhibited higher antiproliferative activities on breast cancer cells compared to previously described non-N-BPs such as clodronate

    PLoS ONE Alerts: New Articles 2009

  • He injected liposomes containing clodronate, a drug that can cause cell death, into the lateral cerebral ventricle.

    Newswise: Latest News 2010

  • He injected liposomes containing clodronate, a drug that can cause cell death, into the lateral cerebral ventricle.

    PhysOrg.com - latest science and technology news stories 2010

  • He injected liposomes containing clodronate, a drug that can cause cell death, into the lateral cerebral ventricle.

    PhysOrg.com - latest science and technology news stories 2010

  • He injected liposomes containing clodronate, a drug that can cause cell death, into the lateral cerebral ventricle.

    Newswise: Latest News 2010

  • Frith, J, Mönkkönen J, Auriola, S, Mönkkönen H, and Rogers MJ (2001) The molecular mechanism of action of the antiresorptive and anti-inflammatory drug clodronate.

    MyLinkVault Newest Links 2009

  • Frith, J, Mönkkönen J, Blackburn GM, Russell RGG, and Rogers MJ (1997) Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5

    MyLinkVault Newest Links 2009

  • Rogers MJ, Azhayev A, Väänänen HK, and Hassinen, I.E. (2002) Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP / ATP translocase by a nonhydrolyzable, adenine-containing metabolite.

    MyLinkVault Newest Links 2009

  • The "clodronate liposomes" video is also posted on youtube:

    MyLinkVault Newest Links 2009

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