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Examples
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This patient was transplanted with the stem cells from a donor who was resistant to HIV because the CCR5 surface co-receptor protein is missing in these cells; thus, leaving the HIV virus unable to enter cells.
Julie Chen, M.D.: Do We Have a Functional Cure for HIV Yet? M.D. Julie Chen 2011
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This patient was transplanted with the stem cells from a donor who was resistant to HIV because the CCR5 surface co-receptor protein is missing in these cells; thus, leaving the HIV virus unable to enter cells.
Julie Chen, M.D.: Do We Have a Functional Cure for HIV Yet? M.D. Julie Chen 2011
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In virology, Progenics is also developing the viral-entry inhibitor PRO 140, a humanized monoclonal antibody which binds to co-receptor CCR5 to inhibit human immunodeficiency virus HIV infection.
unknown title 2011
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Sangamo's ZFNs are designed to permanently modify the DNA sequence encoding CCR5, a co-receptor that enables HIV to enter and infect cells of the immune system.
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By binding to CD3 co-receptor on the T cell, the antibody activates the immune system T cell and instigates the delivery of the T cell cytolytic proteins, perforins and granzymes, into the cancer cells.
unknown title 2011
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ZFN modification disrupts the expression of this key co-receptor for HIV entry and renders cells resistant to HIV infection.
unknown title 2011
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In virology, Progenics is also developing the viral-entry inhibitor PRO 140, a humanized monoclonal antibody which binds to co-receptor CCR5 to inhibit human immunodeficiency virus HIV infection.
unknown title 2011
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For example, the firm's drug blinotumomab binds to the CD3 co-receptor on T cells and to the CD19 membrane protein on the surface of the cancerous B cells, creating an immunological synapse between the immune system's cytotoxic T cells and the cancer cells.
unknown title 2011
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Application of force to other surface molecules including the co-receptor molecule CD8, failed to activate T cells.
Biosingularity Snowcrash 2010
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Drosophila protein arrow, which serves as a co-receptor for wingless, the fly homologue of mammalian Wnt ligands
PLoS ONE Alerts: New Articles Jochen Schulze et al. 2010
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